2012 Buick LaCrosse
4 configurations — EPA fuel economy ratings
| Trim / Variant | City MPG | Hwy MPG | Combined MPG | Fuel | Drive | Engine | Transmission |
|---|---|---|---|---|---|---|---|
| LaCrosse | 17 | 27 | 21 | Regular Gasoline | Front-Wheel Drive | 3.6L 6-cyl | Automatic (S6) |
| LaCrosse | 17 | 27 | 21 | Regular Gasoline | Front-Wheel Drive | 3.6L 6-cyl | Automatic (S6) |
| LaCrosse AWD | 16 | 26 | 20 | Regular Gasoline | All-Wheel Drive | 3.6L 6-cyl | Automatic (S6) |
| LaCrosse eAssist Hybrid | 24 | 35 | 28 | Regular Gasoline | Front-Wheel Drive | 2.4L 4-cyl | Automatic (AV-S6) |