2006 Cadillac STS
4 configurations — EPA fuel economy ratings
| Trim / Variant | City MPG | Hwy MPG | Combined MPG | Fuel | Drive | Engine | Transmission |
|---|---|---|---|---|---|---|---|
| STS | 16 | 25 | 19 | Regular Gasoline | Rear-Wheel Drive | 3.6L 6-cyl | Automatic (S5) |
| STS | 15 | 24 | 18 | Premium Gasoline | Rear-Wheel Drive | 4.6L 8-cyl | Automatic (S5) |
| STS AWD | 15 | 23 | 18 | Regular Gasoline | 4-Wheel or All-Wheel Drive | 3.6L 6-cyl | Automatic (S5) |
| STS AWD | 14 | 21 | 17 | Premium Gasoline | 4-Wheel or All-Wheel Drive | 4.6L 8-cyl | Automatic (S5) |