2000 Ford F150
12 configurations — EPA fuel economy ratings
| Trim / Variant | City MPG | Hwy MPG | Combined MPG | Fuel | Drive | Engine | Transmission |
|---|---|---|---|---|---|---|---|
| F150 Pickup 2WD | 15 | 19 | 16 | Regular Gasoline | Rear-Wheel Drive | 4.2L 6-cyl | Manual 5-spd |
| F150 Pickup 2WD | 14 | 19 | 16 | Regular Gasoline | Rear-Wheel Drive | 4.2L 6-cyl | Automatic 4-spd |
| F150 Pickup 2WD | 13 | 18 | 15 | Regular Gasoline | Rear-Wheel Drive | 5.4L 8-cyl | Automatic 4-spd |
| F150 Pickup 2WD | 13 | 19 | 15 | Regular Gasoline | Rear-Wheel Drive | 4.6L 8-cyl | Manual 5-spd |
| F150 Pickup 2WD | 14 | 19 | 16 | Regular Gasoline | Rear-Wheel Drive | 4.6L 8-cyl | Automatic 4-spd |
| F150 Pickup 2WD CNG | 11 | 15 | 13 | Natural Gas | Rear-Wheel Drive | 5.4L 8-cyl | Automatic 4-spd |
| F150 Pickup 4WD | 12 | 16 | 14 | Regular Gasoline | 4-Wheel or All-Wheel Drive | 5.4L 8-cyl | Automatic 4-spd |
| F150 Pickup 4WD | 13 | 17 | 15 | Regular Gasoline | 4-Wheel or All-Wheel Drive | 4.2L 6-cyl | Manual 5-spd |
| F150 Pickup 4WD | 13 | 17 | 14 | Regular Gasoline | 4-Wheel or All-Wheel Drive | 4.6L 8-cyl | Automatic 4-spd |
| F150 Pickup 4WD | 13 | 17 | 14 | Regular Gasoline | 4-Wheel or All-Wheel Drive | 4.6L 8-cyl | Manual 5-spd |
| F150 Pickup 4WD | 14 | 17 | 15 | Regular Gasoline | 4-Wheel or All-Wheel Drive | 4.2L 6-cyl | Automatic 4-spd |
| Lightning Pickup 2WD | 12 | 15 | 13 | Premium Gasoline | Rear-Wheel Drive | 5.4L 8-cyl Supercharged | Automatic 4-spd |