2006 Lexus GS
3 configurations — EPA fuel economy ratings
| Trim / Variant | City MPG | Hwy MPG | Combined MPG | Fuel | Drive | Engine | Transmission |
|---|---|---|---|---|---|---|---|
| GS 300 4WD | 19 | 25 | 21 | Premium Gasoline | 4-Wheel or All-Wheel Drive | 3L 6-cyl | Automatic (S6) |
| GS 300/GS 430 | 16 | 23 | 19 | Premium Gasoline | Rear-Wheel Drive | 4.3L 8-cyl | Automatic (S6) |
| GS 300/GS 430 | 19 | 27 | 22 | Premium Gasoline | Rear-Wheel Drive | 3L 6-cyl | Automatic (S6) |