2006 Nissan Altima
5 configurations — EPA fuel economy ratings
| Trim / Variant | City MPG | Hwy MPG | Combined MPG | Fuel | Drive | Engine | Transmission |
|---|---|---|---|---|---|---|---|
| Altima | 21 | 27 | 23 | Regular Gasoline | Front-Wheel Drive | 2.5L 4-cyl | Automatic 4-spd |
| Altima | 21 | 29 | 24 | Regular Gasoline | Front-Wheel Drive | 2.5L 4-cyl | Manual 5-spd |
| Altima | 19 | 25 | 21 | Regular Gasoline | Front-Wheel Drive | 3.5L 6-cyl | Manual 5-spd |
| Altima | 18 | 26 | 21 | Regular Gasoline | Front-Wheel Drive | 3.5L 6-cyl | Manual 6-spd |
| Altima | 18 | 27 | 21 | Regular Gasoline | Front-Wheel Drive | 3.5L 6-cyl | Automatic (S5) |