2021 Audi S5
3 configurations — EPA fuel economy ratings
| Trim / Variant | City MPG | Hwy MPG | Combined MPG | Fuel | Drive | Engine | Transmission |
|---|---|---|---|---|---|---|---|
| S5 | 20 | 28 | 23 | Premium Gasoline | All-Wheel Drive | 3L 6-cyl Turbo | Automatic (S8) |
| S5 Cabriolet | 20 | 26 | 22 | Premium Gasoline | All-Wheel Drive | 3L 6-cyl Turbo | Automatic (S8) |
| S5 Sportback | 20 | 28 | 23 | Premium Gasoline | All-Wheel Drive | 3L 6-cyl Turbo | Automatic (S8) |