2019 Mercedes-Benz E-Class
13 configurations — EPA fuel economy ratings
| Trim / Variant | City MPG | Hwy MPG | Combined MPG | Fuel | Drive | Engine | Transmission |
|---|---|---|---|---|---|---|---|
| AMG E53 4matic Plus Hybrid | 21 | 28 | 24 | Premium Gasoline | 4-Wheel Drive | 3L 6-cyl | Automatic 9-spd |
| AMG E53 4matic Plus Convertible Hybrid | 20 | 26 | 23 | Premium Gasoline | 4-Wheel Drive | 3L 6-cyl | Automatic 9-spd |
| AMG E53 4matic Plus Coupe Hybrid | 21 | 28 | 23 | Premium Gasoline | 4-Wheel Drive | 3L 6-cyl | Automatic 9-spd |
| AMG E63 S 4matic | 15 | 23 | 18 | Premium Gasoline | 4-Wheel Drive | 4L 8-cyl Turbo | Automatic 9-spd |
| AMG E63 S 4matic (wagon) | 16 | 23 | 19 | Premium Gasoline | 4-Wheel Drive | 4L 8-cyl Turbo | Automatic 9-spd |
| E300 | 21 | 30 | 25 | Premium Gasoline | Rear-Wheel Drive | 2L 4-cyl Turbo | Automatic 9-spd |
| E300 4matic | 21 | 29 | 24 | Premium Gasoline | 4-Wheel Drive | 2L 4-cyl Turbo | Automatic 9-spd |
| E450 4matic | 20 | 28 | 23 | Premium Gasoline | 4-Wheel Drive | 3L 6-cyl Turbo | Automatic 9-spd |
| E450 4matic (station wagon) | 19 | 26 | 22 | Premium Gasoline | 4-Wheel Drive | 3L 6-cyl Turbo | Automatic 9-spd |
| E450 4matic Convertible | 19 | 26 | 22 | Premium Gasoline | 4-Wheel Drive | 3L 6-cyl Turbo | Automatic 9-spd |
| E450 4matic Coupe | 19 | 26 | 22 | Premium Gasoline | 4-Wheel Drive | 3L 6-cyl Turbo | Automatic 9-spd |
| E450 Convertible | 20 | 27 | 23 | Premium Gasoline | Rear-Wheel Drive | 3L 6-cyl Turbo | Automatic 9-spd |
| E450 Coupe | 20 | 28 | 23 | Premium Gasoline | Rear-Wheel Drive | 3L 6-cyl Turbo | Automatic 9-spd |